- A Case of Myoclonus Presenting as a Side Effect of Amitriptyline
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Jong-Pil Choi, Seong-Soo Park, Joon-Seok Park, Sang-Jun Na
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J Korean Soc Clin Toxicol. 2006;4(2):155-157. Published online December 31, 2006
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 Abstract
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- Myoclonus is manifested in a variety of situations including metabolic derangements, brain lesions, epilepsy, and drugs toxicity. We reported a rare case of amitriptyline-induced myoclonus. A 64-year-old man with a tension-type headache was administered amitriptyline at 15 mg/day. Eight days after initiation of amitriptyline, multifocal myoclonus developed, involving the face and upper extremities. Two hours after the administration of clonazepam at 1 mg, myoclonus resolved completely.
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KSCT
Korean Society of Clinical Toxicology